Boron, a metalloid element that sits next to carbon in the periodic table, has many traits that make it potentially useful as a drug component. Nonetheless, only five FDA-approved drugs contain boron, ...
Replacing a hydrogen atom in the drug with a boron-fluorine compound, boracycle, opens up great opportunities to modify the drug's properties. In this illustration, the boron-fluorine compound has ...
The search for new pharmaceutical drugs by medicinal chemists relies on the synthesis of diverse compound libraries for biological testing. Of the reactions used for this purpose, those involving ...
A new boron-rich compound, manganese diboride, delivers much higher energy density than current solid-rocket materials while remaining stable until intentionally ignited. Its power comes from an ...
Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...
Many of the key proteins for modern medicine and science are poorly soluble. These include numerous signalling proteins and protein hormones, as well as all of the receptors anchored in the cell ...
Iterative synthesis strategies for boron-containing compounds have emerged as powerful tools for the modular construction of complex molecular architectures. Central to these approaches is the use of ...
Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...
A molecular switch is a molecule that can be reversibly shifted between two or more stable states in response to external stimuli, such as a change on pH, light or electric current. These molecules ...
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