Proceedings of the National Academy of Sciences of the United States of America, Vol. 72, No. 6 (Jun., 1975), pp. 1989-1993 (5 pages) ...

At extravascular sites, monocyte/macrophage synthesis of complement protein is thought to be quantitatively important. Lipopolysaccharide(LPS) stimulates the production of C3 and other complement ...

These findings suggest that C3 protects from early glaucomatous damage, a process that may involve EGFR signaling and other immune responses in the optic nerve head. Therefore, therapies that target ...

PASADENA, Calif.--(BUSINESS WIRE)--Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced that it has dosed the first subjects in AROC3-1001, a Phase 1/2 clinical study of ARO-C3, the company’s ...

Medically reviewed by Jamin Brahmbhatt, MD Key Takeaways Complement 3 glomerulopathy (C3G) is diagnosed with a combination of ...

Complement 3 glomerulopathy (C3G) is a glomerular disorder marked by dominant deposition of the C3 complement component within the glomeruli, with minimal or no presence of immunoglobulins and no ...

PASADENA, Calif.--(BUSINESS WIRE)--Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced interim results from Part 1 of AROC3-1001, an ongoing Phase 1/2 clinical study of ARO-C3, the company’s ...

Please provide your email address to receive an email when new articles are posted on . Meningococcal vaccination rates are low among eligible patients with complement component deficiencies, ...