I had a patient recently with a leg infection; he became septic. One of the difficult conditions to treat was that he was hypotensive, heart rate 120, arrhythmic, with 3rd heart sound present. Is it ...

Overview: Digoxin is used for certain heart problems. It helps increase the force of your heartbeat and lower your heart rate. Common side effects can include loss of appetite, nausea, vomiting, ...

Digoxin now deserves to be considered first-line therapy for long-term heart rate control in older patients with permanent atrial fibrillation and symptoms of heart failure, investigators on a new ...

A sensitive (0.2 ng per milliliter), precise (standard deviation 3 to 4 per cent), and specific radioimmunoassay for serum digoxin concentration has been developed. Levels are determined by ...

Digoxin is eliminated mainly by the kidney through glomerular filtration and P-glycoprotein (P-gp) mediated tubular secretion. Toddlers and young children require higher doses of digoxin per kilogram ...

To investigate the effects of phorbol 12-myristate 13-acetate (PMA), a PKC activator, on P-glycoprotein-mediated efflux of digoxin in two cell transport models. PMA (10 μmol/L) did not reduce the ...

Patients with atrial fibrillation (AFib) who are given digoxin to control their symptoms have an increased risk of death, whether or not they have a diagnosis of heart failure, compared with patients ...