Have any humans have been killed by Burmese pythons? What to know Florida's large, invasive residents and their ...

The Florida Fish and Wildlife Conservation Commission will announce the dates for this year's Python Challenge on May 19.

Are Florida's invasive Burmese pythons are more active in warmer months? Signs show signs of cold tolerance, potentially spreading north.

The event now feels like equal parts wildlife management effort, local tradition, and surreal endurance test.

Here's what we know about the 2026 Florida Python Challenge, how the yearly hunt works and a little bit about last year's winner.