Advancing our understanding of the human brain will require new insights into how neural circuitry works in mammals, including laboratory mice. These investigations require monitoring brain activity ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), shoots electrons through a frozen sample. The images formed by the electrons ...

Conventional light microscopy has been instrumental for the study of cells and microorganisms; fluorescence microscopy has enabled visualization of even smaller cell features by selectively adding ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) have developed an innovative microscopy ...

A device that can convert a smartphone or tablet into a fluorescence microscope for less than US $50 is presented in a proof-of-principle study in Scientific Reports. The authors suggest that the ...

Chip technology presents a whole different view on microscopy. Chips are compact and can integrate multiple functionalities. The scaling possibilities could allow chip-based microscopes to be produced ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...