The genome is the complete set of DNA within a cell, encompassing protein-coding genes, non-coding elements and vast tracts of intergenic sequence. In eukaryotes, this information is packaged into ...

Certain epigenetic modifications can directly control how genetic material is packed in the nucleus, RIKEN researchers have ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

For decades, scientists viewed the genome of a newly fertilised egg as a structural 'blank slate' – a disordered tangle of DNA waiting for the embryo to 'wake up' and start reading its own genetic ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...