COPD and gastrointestinal diseases have a significant bidirectional association, with depressive symptoms serving as a key mediator.

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder. Early studies suggested promise, but enthusiasm faded after ...

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major ...

Wellbutrin can interact with several drugs, including other antidepressants, stimulants, and certain diabetes medications. These interactions can increase the risk of side effects or reduce the ...

Depression is often spoken of as if it were a single condition, a uniform experience of sadness, fatigue, or lack of motivation. However, if we look beyond these experiences, we will understand that ...

Highest risk seen for those with both physical frailty and depression; significant additive interaction also seen.

Researchers report that redesigning neurokinin-1 receptor (NK1R) antagonists can restore antidepressant-like effects in animal models. Using machine-learning-guided screening, the team identified ...