Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...

Misha Kudryshev's lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia. Published in The ...

Scientists have identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia. The study points to a potentially new target for ...

Without glucose (red) the hill is too high to climb and so the protein (grey) cannot easily change its path along the dashed line: The light is red. Just like in enzymes, we show that glucose has the ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

Modern eukaryotic cells have proteins that enable chromosome segregation during cell division, new discoveries shed light on their origin in simpler prokaryotic organisms. Modern nucleated (eukaryotic ...