The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

A novel three-dimensional (3D) skeletal muscle model composed of C2C12 mouse myoblasts is described. This model was generated by cultivating myoblasts in suspension using the rotary cell culture ...

Researchers building a model of muscle damage in a cultured system found that components leaking from broken muscle fibers activate ''satellite cells,'' which are muscle stem cells. While attempting ...

New research pinpoints faulty branched-chain amino acid (BCAA) metabolism as a driving force behind sarcopenia, highlighting a potential pathway to slow muscle deterioration and improve aging health.