Targeting epigenetic modifiers and splicing regulators together may offer new acute myeloid leukemia treatment paths

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...
Fred Hutch

RNA “typos” can highlight leukemia cells for immune attack

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...
AZoLifeSciences on MSN

Dual genetic mutations drive RNA mis-splicing and leukemia progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...
The Cornell Daily Sun

Weill Cornell Researchers Develop New Technique to Investigate Impact of Abnormal RNA Splicing on Disease

Researchers in the Landau lab, led by Dr. Dan Landau, hematology and medical oncology, recently developed a new technique to investigate how mutations in RNA splicing can lead to clonal hematopoiesis ...

Short-circuiting pancreatic cancer: A potential RNA therapy

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It's also the most common form of the ...
BioWorld

Genetic code governing how mutations affect mRNA uncovered

Researchers at Monash University in Melbourne, Australia, have uncovered the hidden code governing how genetic mutations affect RNA splicing and result in disease. The researchers were able to ...
Healio

Q&A: Finding a treatment for rare cystic fibrosis splicing mutation

Please provide your email address to receive an email when new articles are posted on . Few patients with cystic fibrosis have a copy of the 3849+10kb C-to-T splicing mutation. Research is planned to ...