Comprehensive analysis maps the intricate regulatory networks of TLR signaling and charts the path from fundamental biology to clinical translation A new review on Toll-like receptors (TLRs) brings ...
Recognition of pathogens by Toll-like receptors (TLR) activate multiple signaling cascades and expression of genes tailored to mount a primary immune response, inflammation, cell survival and ...
(Top) A concise timeline of foundational discoveries in Toll/TLR biology. The discovery and characterization of the Toll/TLR pathway exemplifies how a fundamental biological insight can evolve into a ...