The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, ...

A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become ...

Arctic Therapeutics (ATx) today announced that the first patients have been enrolled in a Phase IIa randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of ...

The key element in the mechanisms in question is tumor necrosis factor-α receptor-1, TNFR1, which becomes pro-inflammatory on binding to the cytokine TNF-α. In one of the situations analyzed, the ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...