The caspases are a family of cytosolic proteases with essential roles in inflammation and apoptosis. Drug discovery efforts have focused on developing molecules directed against the active sites of ...

Unraveling the oncogenic potential of p53 amyloids in colorectal cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

The alternative text for this image may have been generated using AI. Figure 3: Interhelical packing in the Mnt-C tetramer. The alternative text for this image may have been generated using AI.

Scientists have discovered a substance with the capacity to maintain protein p53 stable even when it presents certain mutations that promote the appearance of cancer. An interdisciplinary team of ...