Activity-based proteomics, or activity-based protein profiling (ABPP) is a chemoproteomic strategy that employs modular probes to directly assess the functional state of enzymes within complex …

Abstract Activity-based protein profiling (ABPP) has emerged as a powerful chemical proteomics approach for profiling active amino acid residues, mapping functional proteins, and guiding covalent …

Apr 1, 2020 · Activity-based protein profiling (ABPP) has become an emerging chemical proteomic approach to illustrate the interaction mechanisms between compounds and proteins.

Activity-based protein profiling (ABPP) is a chemical proteomic strategy that provides a direct window into the activity of enzymes within complex biological environments.

Jun 9, 2025 · But now you can use activity-based probes (ABPs) for activity-based protein profiling (ABPP) to not only profile proteins, but profile active proteins. Activity-based probes exploit an …

Furthermore, this book provides updated, comprehensive protocols for utilizing activity-based proteomics profiling to discover new enzymes, detect novel modifications, and identify new drug …

Jul 5, 2007 · Activity-based protein profiling (ABPP), the use of active site-directed chemical probes to monitor enzyme function in complex biological systems, is emerging as a powerful post-genomic …

Apr 9, 2018 · ABPP can be used to identify the protein targets of small molecules and even the active sites of target proteins. This review focuses on the overall workflow of the ABPP technology and on …

Activity-based Protein Profiling (ABPP) is a highly flexible and powerful chemoproteomic technology that utilizes small molecule probes, known as activity-based probes (ABPs), to react with the active sites …

Activity-Based Protein Profiling (ABPP), a function-oriented proteomic technology, offers a novel approach to identifying functionally active proteins through selective labeling using chemical probes.