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  1. Sickle Cell Disease (SCD) Symptoms, Causes & Types

    Aug 13, 2025 · Sickle cell disease (SCD) is an inherited blood disorder. It causes your red blood cells to form into a “C” shape. It can cause pain and serious complications.

  2. Sickle cell disease - Wikipedia

    Sickle cell disease (SCD), also simply called sickle cell, is a group of inherited hemoglobin-related blood disorders. [2] The most common type is known as sickle cell anaemia. [2]

  3. About Sickle Cell Disease | Sickle Cell Disease (SCD) | CDC

    Feb 21, 2025 · Sickle cell disease (SCD) is a group of inherited blood disorders. Abnormal hemoglobin is produced. Red blood cells become hard and sticky and get stuck in small blood vessels, resulting …

  4. Sickle-cell disease - World Health Organization (WHO)

    Aug 6, 2025 · Sickle-cell disease (SCD) is a genetic disorder that affects haemoglobin, the molecule in red blood cells responsible for carrying oxygen. The disease causes red blood cells to become rigid …

  5. What Is Sickle Cell Disease? - NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

  6. Sickle Cell Disease Program | UC Davis Comprehensive Cancer Center

    What is Sickle Cell Disease? Sickle cell disease (SCD) is an inherited blood disorder caused by a change in the gene that helps make hemoglobin — the protein in red blood cells that carries oxygen. …

  7. Sickle Cell Disease (SCD): Symptoms, Causes, and Treatment

    Sep 28, 2025 · Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells. Common symptoms include anemia, fatigue, severe pain, and swelling.

  8. SCD disease burden heavy in US, despite emerging gene therapies

    5 days ago · In the U.S., having sickle cell disease (SCD) continues to place a heavy clinical burden on patients, who often require multiple medications, frequent blood transfusions, and the use of opioids …

  9. Sickle Cell Disease - Johns Hopkins Medicine

    What is sickle cell disease? Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin …

  10. Sickle Cell Disease Fact Sheet - NHLBI, NIH

    Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD.