Some cells divide with a full, closed contractile ring, but some early embryos don’t have that luxury. Their divisions are fast, enormous, and often rely on an open, incomplete actin band. How this “unilateral cytokinesis” works has remained a long‑standing mystery. A new Nature study from Alison Kickuth and colleagues from Jan Brugues lab at the Cluster of Excellence Physics of Life (PoL) at Technische Universität Dresden uncovers the mechanical logic behind it. In zebrafish embryos, microtubul
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